RefPack puts each cited statement in your manuscript beside the passage in the PDF it cites. You decide every finding, and RefPack builds the annotated reference pack your reviewer opens.
The response rate of ECP in acute GvHD exceeds 80% in most studies.5
The source reports 50% to 80%, depending on the organs involved. "Exceeds 80%" overstates it.
Overall response rates to ECP in steroid-refractory acute GvHD ranged from 50% to 80%, with the highest responses in skin involvement and lower rates in gastrointestinal and liver disease.
A reference can be correctly formatted, correctly numbered and still not say what your sentence says. Reviewers check that. Today, so do you: by hand, one PDF at a time.
For every citation, in every draft, you:
Then the same again for the next citation.
Most of this work happens outside any tool. Here is how the usual options compare on the part reviewers care about.
| Option | Checks your statement against the cited PDF | Shows the supporting passage | Records your decisions | Gives your reviewer a deliverable |
|---|---|---|---|---|
| Doing it by hand | Yes, one PDF at a time | You find and highlight it | In a spreadsheet, if you keep one | You assemble it yourself |
| Reference managers | No; they manage your library | No | No | No |
| Reference-list checkers | Check the list, links and retractions, not the claim | No | No | A report on the list |
| AI chat assistants | One question at a time | Sometimes quotes a source | No | No |
| RefPack | Every cited statement in the document | Highlighted, beside the statement | Every decision, with reasons | Annotated manuscript, sources and evidence table |
Three steps. Stop and come back at any point; your project is saved on your computer.
Prepare Review Deliver
Add your manuscript and the reference PDFs it cites. RefPack finds each cited statement and matches every reference to its PDF.
Check each statement against its source with the passage in view. Start an AI search if you want suggestions; every decision stays yours.
…ECP is now widely used. The response rate of ECP in acute GvHD exceeds 80% in most studies.5 In children, no significant adverse effects were associated6…
The source reports 50% to 80%.
Build the reference pack from your saved decisions, preview every page, and send one file.
The reference pack is one ZIP file. Your reviewer opens it without a RefPack account, and every claim leads to its highlighted passage.
“I reviewed these decisions. AI suggestions were aids only, and this pack is not a scientific or regulatory certification.”
Photopheresis in steroid-refractory chronic GvHD
Management of steroid-refractory disease remains difficult, and no single second-line agent is preferred for all patients.
ECP is an established second-line option for patients with steroid-refractory chronic GvHDRef 2 · F-02, particularly with skin and mucosal involvement.
Responses are usually assessed after three months of treatment, and therapy is tapered once a stable response is reached.
Review every finding by hand, or ask AI to suggest the passage. Nothing is sent until you start it.
In the app, the evidence table and the pack, an AI verdict is never shown as your decision.
Approving against the AI, rejecting, or marking a source unavailable asks for a short reason.
Decisions, reasons, who decided and when are listed in the evidence table.
Approve F-05 against the AI?
The AI suggested Partly supported. Choose why you approve it.
The RefPack desktop app reads your files, stores your projects and builds your packs on your computer. Our servers hold your account and project names, not your documents.
AI search, when you start itSelected reference PDFs and cited statements
Your own API key: sent straight from your computer to your provider.
RefPack-funded plans: sent through RefPack's relay, which passes requests on and doesn't keep your documents.
In your browser, refpack.io holds your account, project names and billing.
Claims with their source passages highlighted and labelled, ready for medical, legal and regulatory review.
Find the citation that doesn't hold up before the journal or the client does.
Check another writer's referencing in one pass and send back the evidence with your decisions.
Knowing the limits is part of trusting the result.
Something else? Contact us or read the docs.
RefPack reads your files and stores your projects on your computer. Nothing is sent anywhere until you start an AI search, and RefPack shows what will be sent and where before it goes. Check your client agreements before sending documents to an AI provider.
No. You can review every finding by hand. AI search is optional and only suggests a passage and a verdict.
OpenAI or Azure OpenAI with your own API key, sent straight from your computer. On plans with RefPack-funded searches, requests go through RefPack's relay to the provider.
We don't claim an accuracy figure. Every suggestion shows the passage it is based on, so you can check it quickly, and you make every decision.
Your manuscript as a Word, PowerPoint or PDF file, and the reference PDFs it cites. PDFs need selectable text.
The RefPack desktop app for a Mac with Apple silicon or a Windows 11 PC, and Google Chrome.
You can start free. For a team plan, talk to us.
Start free with your own manuscript, or talk to us about a plan for your team.